My Chargers Chiefs prediction: HT/FT 2/2
Here are the reasons for my betting tip:
- The Chiefs have won each of the last 7 head-to-head matches!
- Kansas City wins almost every game against AFC West rivals!
- The Chargers are weaker than last season!
NFL 2025/26: Chargers – Chiefs Prediction, Stats & Odds

The Chiefs have lost all three of their preseason games! Did their bitter Super Bowl defeat at the beginning of the year throw them off track for good?
Signing up at Bet-at-home to eagerly await the start of the season for Patrick Mahomes & Co. is a smart move for all NFL fans with a penchant for sports betting!
In my Chargers Chiefs prediction, you’ll find out where to find the best odds and which bets have the best chance of success.
Can KC win this AFC West duel in Sao Paulo, Brazil, right at the start of the new season?
Chargers vs. Chiefs predictions:
“Kareem Hunt scores a touchdown” at odds of around 4.33 is the first suggestion ChatGPT gives me in its Chargers Chiefs AI prediction – and also the most lucrative!
In my opinion, this tip makes sense because Kareem Hunt has already scored at least one touchdown in each of his last four NFL games against an AFC West team.
The over-under line for German betting providers is currently at around 46 points – ChatGPT recommends going for the higher value here!
In fact, each of Kansas City’s last eight season opener games against AFC teams has exceeded the points target set by the bookies!
A Chiefs victory at odds of around 1.55, on the other hand, seems like a safe bet. KC needs to make up for a weak preseason and has won each of its last seven head-to-head matchups against the LAC.
What you need to know when betting on Chargers vs. Chiefs
- Kareem Hunt has scored a touchdown in four consecutive AFC games.
- Patrick Mahomes has thrown at least 26 completions in eight of the last ten NFL games in which his team was the favorite.
- Tyler Conklin has scored a touchdown in each of his last two games.
- The Chargers have led at halftime as underdogs in seven consecutive September games.



