Ajax – Inter Milan Tip, AI Prediction & Odds 09/17/2025

Ajax Amsterdam – Inter Milan Tip Champions League, Matchday 1 on Wednesday, 09/17/25 at 9:00 p.m.

I only had to search for a few moments in the Bet365 app and the Bwin app to find a promising Ajax Inter Milan tip.

This is not necessarily due to the clarity of both mobile applications, but rather to the clarity with which Internazionale should dominate this match from the first to the last moment.

Because yes, the 4-5 defeat to Juve still hurts the Milanese soul, but Ajax Amsterdam fans have been plagued by nightmares for many years.

After all, their boys have not won any of their last seven European Cup games against an Italian Serie A club.

Ajax vs. Inter Milan AI predictions:

Our AI model goes one step further than my Ajax vs. Inter Milan prediction and suggests a half-time/full-time score of 2-2.

The profit multiplier of around 3.0x is almost as tempting as the statistics on which this suggestion is based.

Surprisingly, Internazionale has not lost any of its 12 Champions League matches against Dutch teams (9 wins, 3 draws). So will they dictate the game from the first minute on Wednesday?

Predicted chance of winning:

Ajax win
Draw
Inter Milan win
23.3%
21.8%
54.9%

Lautaro Martinez converted a whopping 39% of his shots (nine goals from 23 attempts) in the last edition of the Champions League – the highest conversion rate of any player with at least 15 shots.

Martinez scores at 2.22 is therefore on my shortlist, as the Argentine truly needs very few opportunities to score a goal.

The AI suggestion that both teams will score could easily prove to be a complete flop, with Ajax vs. Inter Milan betting odds averaging 1.62.

Between the 2022/23 and 2024/25 seasons, Inter Milan kept 20 clean sheets in the UEFA Champions League – five more than any other team.

What you need to consider when betting on Ajax vs. Inter Milan

  • Ajax has not won in seven European Cup games against Italian teams – since their 2-1 victory over Juventus in the 2018/19 season.
  • Inter have lost only one of their last 14 Champions League preliminary round games.
  • Between 2022/23 and 2024/25, Inter kept 20 clean sheets in the Champions League, five more than any other team.
  • Kenneth Taylor was Ajax’s top scorer (15 goals) and top assist provider (8 assists) in the 2024/25 season. Since making his Champions League debut in 2022/23, he has also been Ajax’s most successful scorer in European competition with a total of 8 goals.

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