Manchester City – Napoli Tip, Prediction & Odds 09/18/2025

Manchester City – Napoli Tip Champions League, Matchday 1 on Thursday, 09/18/25 at 9:00 p.m.

This is, of course, a very special game for Kevin de Bruyne, as he returns to the Etihad Stadium with his new employer just a few months after his departure.

Incidentally, the Belgian is a great pick for your personal Manchester City vs. Napoli tip, as he has already scored two goals in his last three appearances for SSC.

I’ll now tell you which betting maneuvers our AI recommends, who will be broadcasting the game, and why you shouldn’t ignore the great Betano bonus, especially on Champions League Thursday!

Manchester City vs. Napoli AI predictions:

Our AI is sticking to a home win bet at odds of around 1.65 in its Manchester City vs. Napoli prediction.

I can understand that, as coach Antonio Conte usually focuses his attention on the league and SSC has never shone on the island.

After all, in its long history, Napoli has never won a European Cup match against an English Premier League team in a total of 12 attempts.

Predicted chance of winning:

Manchester City win
Draw
Napoli win
57.4%
23.7%
18.9%

Erling Haaland to score and Haaland to score at least twice are two offers currently available in the comprehensive Bwin app for Manchester City vs. Napoli odds of 1.69 and 3.75 respectively.

Both suggestions also come from our AI model and are well-founded, as the Norwegian seems to be on fire at the moment.

Not only has Haaland scored in each of his last four appearances for the Citizens or Norway, but he has also collected 11 points (9 goals, 2 assists).

What you need to know about Manchester City vs. Napoli betting

  • All four previous City vs. Napoli matches took place in the Champions League group stage: City remained winless in 2011/12 (1D, 1L), but won both games in 2017/18.
  • Napoli are winless in England (12 games: 0W, 3D, 9L) and have already lost to six of their seven opponents there – the exception being a 2-2 draw at Leicester in 2021/22 (UEL).
  • Guardiola has faced Conte seven times, losing more often (4) than he has won (3) – one of only three coaches with a positive record against Pep (alongside Klopp & Luis Enrique).
  • Pep Guardiola is contesting his 17th CL season as a coach, drawing level with José Mourinho. Only Ancelotti (22), Wenger (20), and Ferguson (18) have more appearances.

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