Liverpool – Southampton Tip, AI Prediction & Odds 09/23/2025

Liverpool – Southampton Tip EFL Cup, 3rd Round on Tuesday, 09/23/25 at 9:00 p.m.

As we all know, a good horse only jumps as high as it has to – the Reds seem to have taken this to heart, as each of their last five competitive games has been won by exactly one goal.

Meanwhile, I have so much confidence in my Liverpool Southampton tip that I’m not resorting to a free bet, but instead prefer to dig into my own pocket.

This is because German betting providers seem to be underestimating the chances of LFC conceding another avoidable goal. After all, it’s no coincidence that they have only kept one clean sheet at Anfield Road since the beginning of April.

Liverpool vs. Southampton AI predictions:

In a game in which the Reds will rotate their squad heavily, our digital betting friend’s Liverpool Southampton AI prediction could pay off in full.

1st goal: Southampton may seem like a risky bet at first glance, but the odds of around 4.40 and the fact that the Saints scored the first goal in their last visit to Anfield Road speak in favor of this gamble.

Predicted chance of winning:

Liverpool win
Draw
Southampton win
80.4%
12.4%
7.2%

Both teams to score is another computer-generated suggestion that makes it onto my shortlist, with inflated Liverpool Southampton odds of around 1.90.

Over 2.5 goals, too – and do you know why? Both conditions have been met in 6 of the last 7 competitive meetings between the two sides!

Tuesday’s game could even be the ninth consecutive head-to-head in which the 2.5-goal mark is reached. So these are predictions that make perfect sense.

What you need to know about Liverpool vs. Southampton betting

  • Each of the last 8 direct duels met the over 2.5 goals condition.
  • Southampton scored the interim 1-0 on their last visit to Anfield Road.
  • Liverpool has not been eliminated in the third round of the EFL Cup since 2019/20.
  • Mohamed Salah scored twice in his last appearance against Southampton.

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