NFL 2025/26: Eagles – 49ers Prediction, Stats & Odds
As part of my Eagles 49ers prediction, you will be presented with some interesting betting ideas, with which you can simply benefit better from the attractive Betano odds boosts in case of success.
Because the bookmaker has spiced up selected betting offers for this match.
Primarily, however, I will stick to an unspectacular victory bet on the defending champion on Sunday, which I would at best expand with a slight handicap bet – but maybe with a little luck there will be even more for Philly!
After all, I don’t expect the Eagles to be able to withstand the 49ers’ weakening defense over the season for long. On the other hand, the impetuous Saquon Barkley should be able to gain significant space in almost every running attempt.
Eagles vs. 49ers Predictions:
In my introduction, I already mentioned the player that our separately conducted Eagles 49ers AI prediction also focused on – exactly, the running back of the host!
Saquon Barkley with a touchdown at odds of around 1.75 is also a computer-generated pick that is seriously worth pursuing because it is indeed an excellent choice!
Barkley has recorded at least two touchdowns in three of his last four appearances against NFC West teams when his team was favored in the betting markets in the run-up to the game – and that’s exactly the case again this time!
Each of the last 7 postseason games of the 49ers against NFC West teams could not break the “over” set by the bookmakers – and especially against the strong defense of the Eagles, I honestly see black for the Californians in their own possession!
Consequently, I can also agree with the second AI proposal: Under 44.5 points at odds around 1.85.
Depending on which betting provider with PayPal you prefer, it could also be worthwhile to pay attention to the recommendation San Francisco: Under 2.5 Touchdowns at odds around 1.50.
I don’t think Brock Purdy is up to this defense. Philadelphia, on the other hand, will conjure up enough points on the tableau with its effective style of play to move into the next round unchallenged …
What you need to know about Eagles vs. 49ers betting
- A.J. Brown scored the final touchdown in three of the Eagles’ last four games that followed a loss.
- Saquon Barkley scored at least two touchdowns in three of his last four games, in which his team was the favorite against NFC West opponents.
- Christian McCaffrey scored two or more touchdowns in each of the 49ers’ last three games that followed a loss.
- Brock Purdy recorded at least 23 successful passes (completions) in three of the 49ers’ last four games.
- The 49ers finished 32nd and last in the NFL in the regular season with only 20.0 sacks.
- The 49ers finished 32nd and last in the NFL with 1919 yards (punt yards) in the regular season.
