Leverkusen – Eindhoven Tip Champions League, Matchday 2 on Wednesday, 01.10.2025 at 9:00 p.m.
As the saying goes, you always meet twice in life. And so it happens that Bayer Leverkusen will face former coach Peter Bosz on Matchday 2 of the Champions League. The Dutchman is now under contract with PSV Eindhoven and wants to trip up his former club.
In my Leverkusen Eindhoven prediction, however, I don’t expect this plan to succeed – or rather, only partially.
With the bet “Leverkusen to win & both teams to score,” I have three points in my sights for the Werkself. However, I don’t believe in a shutout victory. Leverkusen has been too shaky on the road in recent weeks.
In fact, Bayer has only kept a clean sheet once in the seven competitive games of the new season so far. And that was in the cup against lower-league SG Großaspach (4-0). So it’s no secret: even under Kasper Hjulmand, the team is still searching for the necessary stability.
So, the first alternative for my Leverkusen Eindhoven prediction is the second part of my combination bet as a standalone tip.
“Both teams to score” also exceeds the 1.50 mark and should be a safe bet for the match between Leverkusen and Eindhoven, regardless of the actual outcome.
Leverkusen – Eindhoven prediction & bets
Another alternative tip I have on my list is “draw at halftime.” The odds of around 2.35 in the Betano app are more than solid and fit the starting position perfectly.
I expect Leverkusen to win, but not in spectacular fashion. A 1-1 draw at halftime, leading to a 2-1 win for the factory club, seems very realistic to me.
Combining these considerations inevitably leads to the bet “Half-time/Full-time Draw/Leverkusen.” Those who are not afraid to take the risk will be rewarded with strong odds of around 5.00.
As a safety-first approach, I also have the bet “PSV to score” up my sleeve. The odds are “only” around 1.40. However, if you keep in mind that the Dutch have scored at least one goal in 19 of their last 20 games, the odds have much more value than they might seem at first glance.
What you need to consider when betting on Leverkusen vs. Eindhoven
- In the past three seasons, Bayer Leverkusen has lost only five of its 54 competitive games at the BayArena. During this period, the team scored an average of 2.5 goals per game.
- PSV Eindhoven travels with an impressive series of eight away wins in competitive games, scoring an average of three goals per game. In the Champions League, however, the Dutch side won only one of their six away games last season.
- The “Both teams to score – Yes” bet has come in on six of Leverkusen’s seven games this season. For PSV, this selection has come in on six of eight games.
- PSV defender Sergino Dest has the second-highest number of successful dribbles per 90 minutes (six) in the Champions League. His teammate Joey Veerman follows in third place (four dribbles).
Leverkusen – Eindhoven: AI tip & odds analysis
Although I have never seen our AI assistant drive his motorhome to the Dutch coast, our Leverkusen Eindhoven AI prediction puts PSV in the spotlight.
The AI’s first selection immediately puts it on a collision course with my own tip. The “Double Chance X2” has odds of around 1.95.
I can’t really understand this reasoning. PSV has won only two of its last five games and didn’t look good at all in its 1-3 Champions League opener against Saint-Gilloise.
I find the second bet from the digital brain much better. At odds of around 1.60, “Over 2.5 goals” is a solid choice at Interwetten Germany, especially since the tip would have been successful in six of Leverkusen’s seven competitive games so far this season. Only in the 1-1 draw against Gladbach did the score remain at two goals.
The AI also wants to bring a result tip into play. If Leverkusen wins exactly 3-1, odds of around 14.0 will be paid out. And don’t forget: Leverkusen’s penultimate home game against Eintracht Frankfurt ended with exactly this result.
The best odds for Leverkusen vs. Eindhoven
PSV’s away game on matchday two follows a weak performance in their Champions League opener against Union Saint-Gilloise. The Belgians earned an xG value of 3.34 in Eindhoven, scored three times and took all three points.
This performance – at home in the Champions League and with odds similar to those for Bayer Leverkusen (1.85) – raises serious questions about PSV’s competitiveness.
Our internal prediction model predicts 2.10 expected goals (xG) for Leverkusen on matchday two, compared to just 1.32 for PSV. The data therefore sees a clear advantage for the hosts.
The bookmakers agree: Eindhoven has been given an Asian handicap of +0.5. A draw or away win is enough to secure the full win. The goal line is set at over/under 3.0 goals.
If there are exactly three goals, bets will be refunded in both directions. For “over” bets, at least four goals are required. Leverkusen’s Bundesliga average of 3.60 goals per game and the league average of 3.49 after five matchdays could argue in favor of over 3.0.
PSV’s last match against a Champions League-caliber team, Ajax, ended 2-2 – which could also steer bettors toward goal bets. However, after a weak performance on the first matchday, caution is advised when it comes to transferring Eredivisie data to the Champions League.
As usual, Patrick Schick is considered the favorite to score for Bayer Leverkusen – both for the home side and overall. The Czech international has already scored twice from the spot and once from open play this season.
The match against PSV could now offer him the chance to double his tally. In the opening game in Copenhagen (2-2), Schick only managed one shot (0.36xG).
Leverkusen vs Eindhoven Match Analysis:
The cities of Leverkusen and Eindhoven are not particularly far apart. However, that does not change the fact that the two teams have only met twice in history.
In the 1994/1995 UEFA Cup season, Bayer won 5-4 at home. In Eindhoven, the game was a completely different story, ending in a 0-0 draw. This means that Leverkusen have never lost to PSV so far.
And this is likely to remain the case, mainly due to the offensive orientation of the factory club. Although Bayer is not consistently successful at the moment, it scores goals on a regular basis. Bayer has scored in 16 of its last 17 games. This includes all competitive games so far this season.
It’s no secret that Peter Bosz likes to play offensively. Accordingly, a rather wild game is likely, with both teams seeking their salvation in attack. It is obvious that this will inevitably lead to one or two defensive gaps.
Leverkusen form check
At the end of September 2025, Bayer Leverkusen is in a phase of searching for consistency.
After five Bundesliga matchdays, they have eight points to their name, with two wins, two draws, and one defeat. With ten goals scored, the offense looks solid, but at the same time, eight goals conceded make it clear that defensive stability is still lacking.
The latest results also underscore this picture: A 2-1 win against Hoffenheim and a 3-3 draw against Bremen alternated with a convincing 3-1 win against Frankfurt and two weaker performances against Gladbach (1-1) and St. Pauli (2-1).
In the Champions League, the Werkself started with a 2-2 draw at Copenhagen, which also reflects their current fluctuating form. Coach Kasper Hjulmand, who has been in charge since the beginning of September, is working to find the right balance between attacking intent and defensive solidity.
Eindhoven form check
PSV Eindhoven are one of the favorites in the Eredivisie at the end of September. After seven matchdays, the team has collected 16 points (5 wins, 1 draw, 1 defeat) with a goal difference of 21:11, putting them in second place.
The figures reflect a strong offense, but at the same time, the eleven goals conceded point to stability issues in defense.
In recent competitive games, PSV has shown its offensive prowess with a spectacular 5-3 win in Nijmegen and a 2-1 win at Excelsior, as well as a 2-2 draw against Ajax — but its Champions League debut was sobering (1-3 against Union Saint-Gilloise).
Offensive leaders such as Joey Veerman and Ruben van Bommel are currently tied at the top of the scoring charts (3 goals each), while Ricardo Pepi has made a comeback with goals in important games.
Coach Peter Bosz seems keen to find the balance between attacking power and compactness — PSV look dangerous in front of goal, but are not yet flawless.
