Napoli – Pisa Prediction Serie A, Matchday 4 on Monday, 09/22/25 at 8:45 p.m.
When you find yourself in a duel with the massive Erling Haaland, you have to pull out a damn long scythe to touch the ball and not the Norwegian when sliding in.
SSC captain Di Lorenzo will now have learned this lesson, leaving his team a man down after committing a last-ditch tackle. The subsequent goals conceded were a logical consequence of this action.
However, my Napoli vs. Pisa prediction for Monday night’s Italian game, posted on Merkur Bets Germany, remains unaffected: a win for the Neapolitans without conceding a goal.
This is because the Azzurri are a very consistent team when it comes to Serie A home games. After all, they haven’t lost at the Stadio Diego Armando Maradona in 12 league games and have even kept a clean sheet in half of those games.
Napoli vs. Pisa AI predictions:
Right from the start, our Napoli Pisa AI prediction suggested that the hosts would win and that there would be fewer than three goals.
I quickly thought of the perfect bet offer in the Bwin app: Napoli to win 1-0, 2-0, or 3-0, which promises a 2.2x win multiplier and can be found under the category “Exact score (multiple options)”.
Predicted chance of winning:
| Napoli win |
Draw |
Pisa win |
| 74.1% |
18.1% |
7.9% |
1. Goalscorer: Kevin De Bruyne is almost a digital stroke of genius at average Napoli Pisa odds of 7.50. The Belgian has already scored in two of his first three Serie A appearances for SSC and is also well rested.
For tactical reasons, the Belgian was recently substituted after just 20 minutes to make way for a defender.
I would also select under 3.5 goals at around 1.40 in a comprehensive betting app if I were generally skeptical about a Neapolitan victory. Either way, there should be very few goals scored on Monday evening.
What you need to consider when betting on Napoli vs. Pisa
- Napoli are unbeaten in 12 Serie A home games (9W, 3D) and have kept six clean sheets in that run.
- Napoli have scored the first goal in 15 of their last 20 home league games.
- Only one of Pisa’s last five away games has seen more than 2.5 goals scored.
- Pisa is the only Serie A team that has not scored a goal after halftime.



