US Open betting: Winner odds & favorites – Who will win the 2025 US Open?

Who will win the 2025 US Open? The bookmakers’ US Open betting odds have two big favorites: Jannik Sinner and Carlos Alcaraz.

The two lead the world rankings (Sinner at number 1, Alcaraz at number 2) and have contested the finals of the last two Grand Slam tournaments (French Open and Wimbledon). Will there be a third final battle in New York or will there be a different US Open champion?

US Open betting 2025: Alcaraz and Sinner the favorites in the men’s singles

Who will win the US Open 2025? For the men’s singles, sports betting providers are answering this question with two names: Carlos Alcaraz and Jannik Sinner!

The two exceptional players, who have both already won at Flushing Meadows – Alcaraz in 2022 and Sinner last year – are dominating the big tennis stages this year.

At the last two Grand Slam tournaments – the French Open in Paris and Wimbledon – Sinner and Alcaraz reached the final and battled it out for the tournament victory. Carlos Alcaraz won in Paris in an epic 5-set fight, and Jannik Sinner took his revenge shortly afterwards on the hallowed turf.

Will the next Alcaraz/Sinner final follow in New York?

The US Open betting and tournament winner odds certainly look that way in the run-up to the tournament. The Italian and the Spaniard are clearly and convincingly leading the bookmakers’ “Who will win the 2025 US Open” rankings.

It is fitting that both recently reached the final of the Masters tournament in Cincinnati. However, Sinner had to withdraw due to illness.

The US Open winner odds for Djokovic

Behind Sinner and Alcaraz, a certain Novak Djokovic is listed as the first challenger to the top duo in the US Open betting before the tournament begins.

Djokovic has reached the semifinals in all three Grand Slam tournaments this year. Not even Alcaraz managed that, and only Sinner did better, reaching the final in all three majors.

However, the veteran has not played in a tournament since his semifinal exit at Wimbledon in July. Djokovic has opted out of the Masters events in Toronto and Cincinnati.

As a result, the 38-year-old has slipped slightly in the world rankings and is now only ranked 7th in the world. This is also reflected in his seeding at the US Open.

However, Djokovic, who arrives in New York completely rested, knows how to win at Flushing Meadows: in 2023, he triumphed for the fourth time in the concrete bowl known as Arthur Ashe Stadium. That was also his 24th and, to date, last Grand Slam title.

 

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Who are the other US Open favorites?

Behind the top trio, there are several other US Open favorites and dark horses.

Given his recent results, Alexander Zverev could be a contender for the silver trophy. In any case, Zverev is among the favorites in the US Open winner odds before the tournament begins.

Zverev, seeded number 3 in the US Open draw, has overcome his mental slump and recently reached the semifinals at the Masters 1000 tournaments in Toronto and Cincinnati.

Along with Zverev, there is a long list of promising co-favorites to win the title in New York.

Ben Shelton could prove to be an insider tip in the 2025 US Open betting. The young American recently won the Toronto Masters and climbed to number 6 in the world rankings.
In addition to Shelton, who reached the semifinals at Flushing Meadows in 2023, there are other US stars who could secure a home victory, such as Taylor Fritz (last year’s finalist & fourth seed), Frances Tiafoe (US Open semifinalist in 2022 and 2024) and Tommy Paul.

Also in the “co-favorites” category are Alex de Minaur (AUS/ATP No. 8), Lorenzo Musetti (ITA/10th) and Russia’s Daniil Medvedev – even though things have not gone as planned recently for the 2021 US Open winner.

The same applies to the Scandinavian duo Holger Rune (DEN) and Caspar Ruud (NOR), who can only be counted among the extended circle of this year’s US Open favorites with a lot of goodwill. They are listed in positions 11 and 12 in the seedings.

The best bets for the 2025 US Open

As soon as a major tennis event such as the 2025 US Open is coming up, the interest in tennis among sports betting fans increases even more. Especially for the hard court classic in New York.

Which tennis bets are the most popular, and which are suitable for the Grand Slam highlight in Flushing Meadows?

Here is a compact overview: These are the 4 best US Open bets for 2025.

  • 1. Win bet
  • 2. Set bets
  • 3. Tie-break
  • 4. Long-term bets

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