Tottenham – Villarreal Tip, AI Prediction & Odds 09/16/2025

Tottenham – Villarreal Tip Champions League, Matchday 1 on Tuesday, 09/16/2025 at 9:00 p.m.

Exciting English-Spanish duel in London! The Spurs are hoping for a successful start to their first CL season since 2022/23 against their guests from Spain. For our Tottenham Villarreal tip, I have chosen the classic home win bet, which brings odds of around 1.80 at Bet365.

Even though Spurs are “only” allowed to start in the Champions League because of their Europa League triumph, I see the English side as favorites against the current fifth-placed team in La Liga. After all, Spurs are third in England.

Apart from the 0-1 slip-up against Bournemouth, Spurs have made a very good start with three wins from four games. They have scored eight goals in attack, and when Tottenham scores, it’s always at least twice.

After two wins against lesser-known teams, Villarreal has recently suffered setbacks. The draw at Celta Vigo was followed by a 0-2 defeat at Atletico Madrid over the weekend. The “Submarino Amarillo” is therefore struggling away from home.

Tottenham vs. Villarreal AI predictions:

Our in-house AI, as well as our bookies, including the new reputable betting providers, have the hosts as favorites. With an implied probability of 70 percent, all Champions League predictions are predicting a Tottenham win. As mentioned above, so am I.

However, Thomas Frank’s team was also considered a similar favorite against Bournemouth, but lost 0-1. That’s why our AI also spits out an over/under bet as a promising Tottenham Villarreal bet.

Here you have two betting options: firstly, our AI tool expects 3.45 goals in the game. An over 2.5 goals tip not only gives you odds of 1.73 at Interwetten, but you can also secure the Interwetten betting bonus, which gives you, as a Wettfreunde reader, an €11 free bet in addition to the new customer bonus.

Since the expected goals for Villarreal are 1.01, a “both teams to score” bet would also be appropriate. The odds for this are around 1.65. If you combine both betting tips, Betano will give you odds of around 2.10 for the over 2.5 goals and both teams to score bet.

What you need to know about Tottenham vs. Villarreal betting

  • Tottenham has won only two of its seven opening games in the European Cup (2D, 3L), with both wins coming in its last two home games.
  • Between April 27, 2025, and August 31, 2025, Villareal earned 24 out of a possible 27 points in La Liga.
  • 42 percent of Tottenham’s goals in the UEFA Champions League (since 1992/93) have been scored by Harry Kane or Son Heung-min (37/89). Following the departure of the pair, Richarlison (2) is the only current Tottenham player to have scored more than one goal for the club in this competition.
  • Tottenham have lost only one of their last 20 European home games. During that period, Spurs have scored 2.36 goals per game and conceded just 0.70.

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