Inter Milan – Sassuolo Tip, AI Prediction & Odds 09/21/2025

Inter Milan – Sassuolo Tip Serie A, Matchday 4 on Sunday, 09/21/25 at 8:45 p.m.

Did you know that of the last 5 Serie A games between these two teams, the newly promoted side has won more than the glamorous club from the fashion capital?

My Inter Sassuolo tip takes this fact into account, as well as the most interesting offers in the best sports betting apps across Germany.

In any case, Domenico Berardi has visibly declined compared to a few years ago and is no longer directing the Neroverdi’s offense as successfully as he did in the 2020/21 or 2021/22 seasons.

Consequently, I think that if the hosts perform as they did against Ajax during the week, it could be a one-sided affair.

Inter Milan vs. Sassuolo AI predictions:

Our Inter Milan AI prediction was insightful, as it revealed three recommendations that I can share with you without hesitation.

1st goal: Hakan Calhanoglu at monster odds of around 8.00 is a truly spectacular suggestion, where the risk-reward ratio simply couldn’t be better.

The Turkish player scored two goals himself last week and provided the assist for two more during the week. Whenever the Milan fans cheer a goal, their playmaker usually has a hand in it.

Predicted chance of winning:

Inter Milan win
Draw
Sassuolo win
72.6%
18%
9.4%

Inter wins to nil at odds of 1.98 also seems convincing to me. In any case, I would put the probability of success for this bet at over 60 percent. Sassuolo’s attack simply lacks punch in the top flight.

1st goal: Inter Milan is a good bet for those who are putting together a long combination bet slip and are still looking for a safe 1.30 odds. That’s because the Milanese are true experts when it comes to scoring the first goal at San Siro.

What you need to know when betting on Inter Milan vs. Sassuolo

  • In five of Inter’s last seven home games, a goal was scored within the first 20 minutes.
  • In six of Inter’s last nine league games, only one team scored.
  • Sassuolo has conceded at least two goals in eight of its last eleven Serie A games.
  • After three matchdays, Sassuolo’s games had the lowest average number of corners in the league (7.33 per game).

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