Genoa – Lazio Rome Tip Serie A, Matchday 5 on Monday, 09/29/25 at 8:45 p.m.
I didn’t have to stare at the betting odds of the many old and new sports betting providers for long to be able to place a reasonable Genoa Lazio Rome tip here.
Yes, the Romans have just lost the Derby della Capitale and, after their crushing victory over Hellas Verona, seem to have forgotten how to pose a threat in front of the opponent’s goal.
On the other hand, the Grifoni are a club that has won only one league game since mid-April and is, at best, a mid-table team.
In short: In my opinion, the Lazio odds for an away win estimated by Interwetten and Winamax Germany are worth a try!
Genoa vs. Lazio Rome AI predictions:
The Genoa Lazio Rome AI prediction makes me extremely confident about my own prediction for this match. Because it even goes one step further!
Half-time/full-time 2/2 is the suggestion from our AI model, which is by no means a bold one at odds of around 3.95. After all, Lazio has won each of the last four direct duels.
Predicted chance of winning:
| Genoa win |
Draw |
Lazio Rome win |
| 30.9% |
30% |
39.1% |
However, there is another striking trend in the last four matches that can be used to derive an additional, promising bet for this encounter.
We are referring to a Lazio win without conceding a goal at an equally impressive average of 3.80. This would be the capital club’s fifth consecutive win of this kind over the Grifoni.
1. First goalscorer: Taty Castellanos is another good suggestion at odds of around 7.60 – but only for the more daring among you. This goal bet is reasonable because no Lazio player has been more dangerous in front of goal so far (1 goal, 2 assists).
What you need to know when betting on Genoa vs. Lazio Rome
- There has been no BTS in any of the last 5 direct duels
- There has also been no BTS in Lazio Rome’s last 5 Serie A games
- Genoa has not won any of its last 5 Serie A home games
- Lazio Rome could beat Genoa to nil for the fifth competitive game in a row



